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The normal role of Activated Protein C in maintaining homeostasis and its relevance to critical illness
Thrombin is a multifunctional protein, with procoagulant, inflammatory and anticoagulant effects. Binding of thrombin to thrombomodulin results in activation of Protein C and initiation of the Activated Protein C anticoagulant pathway, a process that is augmented by the endothelial cell Protein C re...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2001
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3300084/ https://www.ncbi.nlm.nih.gov/pubmed/11379986 http://dx.doi.org/10.1186/cc1333 |