Cargando…

Genomic approaches to drug target discovery using mouse models

Detalles Bibliográficos
Autor principal:	Morris, DW
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2003
Materias:	Oral Presentation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3300177/ http://dx.doi.org/10.1186/bcr716

Ejemplares similares

Role of animal models in oncology drug discovery
por: Kumar, R
Publicado: (2003)

The role of systems modeling in drug discovery and predictive health
por: Voit, Eberhard O
Publicado: (2010)

Antimalarial drug discovery: targeting the hypnozoite for new radical curative agent
por: Yeung, Bryan
Publicado: (2012)

Mouse models for pretesting of immunotherapeutic strategies for cancer patients
por: Burchell, JM, et al.
Publicado: (2003)

OA02.08. Chick embryo model an experimental model for drug discovery in ayurveda.
por: Tomar, Ekta, et al.
Publicado: (2013)

Target discovery in the postgenomic era
por: Friedman, L, et al.
Publicado: (2003)

Drug discovery in the p53 pathway
por: Lane, DP, et al.
Publicado: (2000)

Towards a patient-based drug discovery
por: Schreiber, Stuart L
Publicado: (2012)

Using genomic similarities and differences to interpret mouse models of human development and cancer
por: Stubbs, L, et al.
Publicado: (2003)

Pluripotent stem cells for pathological modelling of Hutchinson-Gilford Progeria Syndrome (HGPS) and drug discovery
por: Nissan, Xavier
Publicado: (2015)

Natural product-likeness score and its applications in the drug discovery process
por: Ertl, Peter, et al.
Publicado: (2008)

Genetically modified cancer models: the value of luciferase-tagged tumors and in vivo luciferase-based reporter assays in oncology drug discovery
por: Yang, W, et al.
Publicado: (2003)

CADDSuite – a workflow-enabled suite of open-source tools for drug discovery
por: Kohlbacher, Oliver
Publicado: (2012)

Use of mouse models to validate and therapeutically target transforming growth factor beta as an important player in breast cancer progression
por: Wakefield, LM, et al.
Publicado: (2003)

A finite element foot model for simulating muscle imbalances
por: Ledoux, William R, et al.
Publicado: (2008)

S9.3d Antivirulence drug discovery to disarm Candida albicans with metabolites from myxobacteria.
por: Vij, Raghav, et al.
Publicado: (2022)

Preneoplasia in mouse models
por: Medina, D
Publicado: (2003)

High-throughput targeted SNP discovery using Next Generation Sequencing (NGS) in few selected candidate genes in Eucalyptus camaldulensis
por: Hendre, Prasad Suresh, et al.
Publicado: (2011)

Charting the regulatory landscape of the mouse genome in vivo
por: Symmons, Orsolva, et al.
Publicado: (2013)

The mouse in preclinical trials: transgenic, carcinogen-induced, or xenograph models – which to use?
por: Brown, P
Publicado: (2003)

Targeting protein dynamics in drug design
por: Wade, Rebecca C
Publicado: (2013)

Predicting drug polypharmacology using a novel surface property similarity-based approach
por: Perez-Nueno, Violeta I, et al.
Publicado: (2011)

Experimental mouse model of tuberculous uveitis
por: Abhishek, Sudhanshu, et al.
Publicado: (2014)

High-throughput sequencing of the DBA/2J mouse genome
por: Wang, Xusheng, et al.
Publicado: (2010)

New cytokinin derivatives – their discovery, development and use for micropropagation of endangered tree species
por: Dolezal, Karel, et al.
Publicado: (2011)

Functional genomic approaches to breast cancer
por: Bernards, R
Publicado: (2005)

Targeted genome and epigenome editing using engineered TALE and CRISPR/Cas9 technologies
por: Gersbach, Charles A
Publicado: (2014)

Semi-supervised class discovery using quantitative phenotypes – CVD as a case study
por: Steinfeld, Israel, et al.
Publicado: (2007)

Molecular targets for PDE inhibitor-mediated improvement of cardiac dysfunction in the mdx mouse?
por: Adamo, Candace M, et al.
Publicado: (2011)

Genomic scale analysis of lateral gene transfer in Apicomplexan parasites: insights into early eukaryotic evolution, host-pathogen interaction and drug target development
por: Peixoto, Lucia, et al.
Publicado: (2007)

The role of IL-17 in the development of arthritis in mouse models
por: Iwakura, Y, et al.
Publicado: (2003)

Mouse models of human breast cancer: evolution or convolution?
por: Green, JE
Publicado: (2003)

Mouse models for BRCA1-associated breast cancer
por: Wang, R-H, et al.
Publicado: (2003)

Genetically engineered mouse models of human breast cancer
por: Jensen, RA
Publicado: (2003)

Ion channels: their discovery, their function, and their role in disease
por: Neher, Erwin
Publicado: (2014)

Effects of interference with GATA-3 expression by target-specific DNAzyme treatment on disease progression in a subacute oxazolone-induced mouse model of atopic dermatitis
por: Ibrahim, Rouba, et al.
Publicado: (2015)

A non-linear beta-binomial regression model for mapping qlqc-30 to the eq-5d in lung cancer patients: a comparison with existing approaches
por: Khan, Iftekhar, et al.
Publicado: (2013)

Reversibility and progression in conditional transgenic mouse models of breast cancer
por: Chodosh, LA, et al.
Publicado: (2003)

Imaging mouse models of breast cancer with positron emission tomography
por: Cherry, S, et al.
Publicado: (2003)

Expression of aquaporins in a transgenic mouse model of Alzheimer's disease
por: Chan, Sic L, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_ghs597bj27aqcpp84taq6nc7ek