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Carbamate derivatives and sesquiterpenoids from the South China Sea gorgonian Melitodes squamata
Five carbamate derivatives, obtucarbamates C and D (1, 2), dimethyl ((carbonylbis(azanediyl))bis(2-methyl-5,1-phenylene))dicarbamate (3), obtucarbamates A and B (4, 5), and four aromadendrane-type sesquiterpenoids, (+)-4β-N-methenetauryl-10β-methoxy-1β,5α,6β,7β-aromadendrane (6), (−)-4β-N-methenetau...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302077/ https://www.ncbi.nlm.nih.gov/pubmed/22423284 http://dx.doi.org/10.3762/bjoc.8.18 |
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author | Huang, Li-Si He, Fei Huang, Hui Zhang, Xiao-Yong Qi, Shu-Hua |
author_facet | Huang, Li-Si He, Fei Huang, Hui Zhang, Xiao-Yong Qi, Shu-Hua |
author_sort | Huang, Li-Si |
collection | PubMed |
description | Five carbamate derivatives, obtucarbamates C and D (1, 2), dimethyl ((carbonylbis(azanediyl))bis(2-methyl-5,1-phenylene))dicarbamate (3), obtucarbamates A and B (4, 5), and four aromadendrane-type sesquiterpenoids, (+)-4β-N-methenetauryl-10β-methoxy-1β,5α,6β,7β-aromadendrane (6), (−)-4β-N-methenetauryl-10β-methoxy-1β,5β,6α,7α-aromadendrane (7), (−)-4α,10β-aromadendranediol (8), (+)-4β,10β-aromadendranediol (9) were obtained from the South China Sea gorgonian coral Melitodes squamata Nutting. Compounds 1, 2, 6, and 7 were new, and their structures were established by spectroscopic analyses. Compounds 6 and 7 contained a taurine group that was rarely found in marine natural compounds, and 7 showed moderate antibacterial activity. The possible biosynthesis routes of 1–5 were conjectured. |
format | Online Article Text |
id | pubmed-3302077 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Beilstein-Institut |
record_format | MEDLINE/PubMed |
spelling | pubmed-33020772012-03-15 Carbamate derivatives and sesquiterpenoids from the South China Sea gorgonian Melitodes squamata Huang, Li-Si He, Fei Huang, Hui Zhang, Xiao-Yong Qi, Shu-Hua Beilstein J Org Chem Full Research Paper Five carbamate derivatives, obtucarbamates C and D (1, 2), dimethyl ((carbonylbis(azanediyl))bis(2-methyl-5,1-phenylene))dicarbamate (3), obtucarbamates A and B (4, 5), and four aromadendrane-type sesquiterpenoids, (+)-4β-N-methenetauryl-10β-methoxy-1β,5α,6β,7β-aromadendrane (6), (−)-4β-N-methenetauryl-10β-methoxy-1β,5β,6α,7α-aromadendrane (7), (−)-4α,10β-aromadendranediol (8), (+)-4β,10β-aromadendranediol (9) were obtained from the South China Sea gorgonian coral Melitodes squamata Nutting. Compounds 1, 2, 6, and 7 were new, and their structures were established by spectroscopic analyses. Compounds 6 and 7 contained a taurine group that was rarely found in marine natural compounds, and 7 showed moderate antibacterial activity. The possible biosynthesis routes of 1–5 were conjectured. Beilstein-Institut 2012-01-31 /pmc/articles/PMC3302077/ /pubmed/22423284 http://dx.doi.org/10.3762/bjoc.8.18 Text en Copyright © 2012, Huang et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms) |
spellingShingle | Full Research Paper Huang, Li-Si He, Fei Huang, Hui Zhang, Xiao-Yong Qi, Shu-Hua Carbamate derivatives and sesquiterpenoids from the South China Sea gorgonian Melitodes squamata |
title | Carbamate derivatives and sesquiterpenoids from the South China Sea gorgonian Melitodes squamata |
title_full | Carbamate derivatives and sesquiterpenoids from the South China Sea gorgonian Melitodes squamata |
title_fullStr | Carbamate derivatives and sesquiterpenoids from the South China Sea gorgonian Melitodes squamata |
title_full_unstemmed | Carbamate derivatives and sesquiterpenoids from the South China Sea gorgonian Melitodes squamata |
title_short | Carbamate derivatives and sesquiterpenoids from the South China Sea gorgonian Melitodes squamata |
title_sort | carbamate derivatives and sesquiterpenoids from the south china sea gorgonian melitodes squamata |
topic | Full Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302077/ https://www.ncbi.nlm.nih.gov/pubmed/22423284 http://dx.doi.org/10.3762/bjoc.8.18 |
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