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Regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heating
The multicomponent reaction of 5-aminopyrazole derivatives with cyclic 1,3-dicarbonyl compounds and dimethylformamide dimethylacetal (DMFDMA) in DMF at 150 °C under controlled microwave heating afforded regioselectively 8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-ones 6 rather than the corresponding...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302079/ https://www.ncbi.nlm.nih.gov/pubmed/22423269 http://dx.doi.org/10.3762/bjoc.8.3 |
| _version_ | 1782226631160496128 |
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| author | Sadek, Kamal Usef Mekheimer, Ramadan Ahmed Mohamed, Tahany Mahmoud Moustafa, Moustafa Sherief Elnagdi, Mohamed Hilmy |
| author_facet | Sadek, Kamal Usef Mekheimer, Ramadan Ahmed Mohamed, Tahany Mahmoud Moustafa, Moustafa Sherief Elnagdi, Mohamed Hilmy |
| author_sort | Sadek, Kamal Usef |
| collection | PubMed |
| description | The multicomponent reaction of 5-aminopyrazole derivatives with cyclic 1,3-dicarbonyl compounds and dimethylformamide dimethylacetal (DMFDMA) in DMF at 150 °C under controlled microwave heating afforded regioselectively 8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-ones 6 rather than the corresponding dihydropyrazolo[5,1-b]quinazolin-8(5H)-ones 4. |
| format | Online Article Text |
| id | pubmed-3302079 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2012 |
| publisher | Beilstein-Institut |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-33020792012-03-15 Regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heating Sadek, Kamal Usef Mekheimer, Ramadan Ahmed Mohamed, Tahany Mahmoud Moustafa, Moustafa Sherief Elnagdi, Mohamed Hilmy Beilstein J Org Chem Full Research Paper The multicomponent reaction of 5-aminopyrazole derivatives with cyclic 1,3-dicarbonyl compounds and dimethylformamide dimethylacetal (DMFDMA) in DMF at 150 °C under controlled microwave heating afforded regioselectively 8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-ones 6 rather than the corresponding dihydropyrazolo[5,1-b]quinazolin-8(5H)-ones 4. Beilstein-Institut 2012-01-04 /pmc/articles/PMC3302079/ /pubmed/22423269 http://dx.doi.org/10.3762/bjoc.8.3 Text en Copyright © 2012, Sadek et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms) |
| spellingShingle | Full Research Paper Sadek, Kamal Usef Mekheimer, Ramadan Ahmed Mohamed, Tahany Mahmoud Moustafa, Moustafa Sherief Elnagdi, Mohamed Hilmy Regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heating |
| title | Regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heating |
| title_full | Regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heating |
| title_fullStr | Regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heating |
| title_full_unstemmed | Regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heating |
| title_short | Regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heating |
| title_sort | regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heating |
| topic | Full Research Paper |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302079/ https://www.ncbi.nlm.nih.gov/pubmed/22423269 http://dx.doi.org/10.3762/bjoc.8.3 |
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