Dioxane dibromide mediated bromination of substituted coumarins under solvent-free conditions

An efficient solvent-free protocol for regioselective bromination of substituted coumarins has been developed by using dioxane dibromide as the solid brominating agent. The efficacy of the solvent-free protocol has been established. The effects of the electronic nature and location of the substituen...

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Autores principales: Chaudhuri, Subrata Kumar, Roy, Sanchita, Bhar, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2012
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302096/
https://www.ncbi.nlm.nih.gov/pubmed/22423301
http://dx.doi.org/10.3762/bjoc.8.35
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author Chaudhuri, Subrata Kumar
Roy, Sanchita
Bhar, Sanjay
author_facet Chaudhuri, Subrata Kumar
Roy, Sanchita
Bhar, Sanjay
author_sort Chaudhuri, Subrata Kumar
collection PubMed
description An efficient solvent-free protocol for regioselective bromination of substituted coumarins has been developed by using dioxane dibromide as the solid brominating agent. The efficacy of the solvent-free protocol has been established. The effects of the electronic nature and location of the substituents on the outcome of the reaction have been rationalized with a proposed mechanism.
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spelling pubmed-33020962012-03-15 Dioxane dibromide mediated bromination of substituted coumarins under solvent-free conditions Chaudhuri, Subrata Kumar Roy, Sanchita Bhar, Sanjay Beilstein J Org Chem Full Research Paper An efficient solvent-free protocol for regioselective bromination of substituted coumarins has been developed by using dioxane dibromide as the solid brominating agent. The efficacy of the solvent-free protocol has been established. The effects of the electronic nature and location of the substituents on the outcome of the reaction have been rationalized with a proposed mechanism. Beilstein-Institut 2012-02-29 /pmc/articles/PMC3302096/ /pubmed/22423301 http://dx.doi.org/10.3762/bjoc.8.35 Text en Copyright © 2012, Chaudhuri et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Chaudhuri, Subrata Kumar
Roy, Sanchita
Bhar, Sanjay
Dioxane dibromide mediated bromination of substituted coumarins under solvent-free conditions
title Dioxane dibromide mediated bromination of substituted coumarins under solvent-free conditions
title_full Dioxane dibromide mediated bromination of substituted coumarins under solvent-free conditions
title_fullStr Dioxane dibromide mediated bromination of substituted coumarins under solvent-free conditions
title_full_unstemmed Dioxane dibromide mediated bromination of substituted coumarins under solvent-free conditions
title_short Dioxane dibromide mediated bromination of substituted coumarins under solvent-free conditions
title_sort dioxane dibromide mediated bromination of substituted coumarins under solvent-free conditions
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302096/
https://www.ncbi.nlm.nih.gov/pubmed/22423301
http://dx.doi.org/10.3762/bjoc.8.35
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AT roysanchita dioxanedibromidemediatedbrominationofsubstitutedcoumarinsundersolventfreeconditions
AT bharsanjay dioxanedibromidemediatedbrominationofsubstitutedcoumarinsundersolventfreeconditions

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