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Effect of Chronic L-Dopa or Melatonin Treatments after Dopamine Deafferentation in Rats: Dyskinesia, Motor Performance, and Cytological Analysis

The present study examines the ability of melatonin to protect striatal dopaminergic loss induced by 6-OHDA in a rat model of Parkinson's disease, comparing the results with L-DOPA-treated rats. The drugs were administered orally daily for a month, their therapeutic or dyskinetic effects were a...

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Detalles Bibliográficos
Autores principales: Gutierrez-Valdez, Ana Luisa, Anaya-Martínez, Verónica, Ordoñez-Librado, José Luis, García-Ruiz, Ricardo, Torres-Esquivel, Carmen, Moreno-Rivera, Montserrat, Sánchez-Betancourt, Javier, Montiel-Flores, Enrique, Avila-Costa, Maria Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302121/
https://www.ncbi.nlm.nih.gov/pubmed/22462019
http://dx.doi.org/10.5402/2012/360379