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Effect of Chronic L-Dopa or Melatonin Treatments after Dopamine Deafferentation in Rats: Dyskinesia, Motor Performance, and Cytological Analysis
The present study examines the ability of melatonin to protect striatal dopaminergic loss induced by 6-OHDA in a rat model of Parkinson's disease, comparing the results with L-DOPA-treated rats. The drugs were administered orally daily for a month, their therapeutic or dyskinetic effects were a...
Autores principales: | Gutierrez-Valdez, Ana Luisa, Anaya-Martínez, Verónica, Ordoñez-Librado, José Luis, García-Ruiz, Ricardo, Torres-Esquivel, Carmen, Moreno-Rivera, Montserrat, Sánchez-Betancourt, Javier, Montiel-Flores, Enrique, Avila-Costa, Maria Rosa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scholarly Research Network
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302121/ https://www.ncbi.nlm.nih.gov/pubmed/22462019 http://dx.doi.org/10.5402/2012/360379 |
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