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Characterization of a new animal model of metabolic syndrome: the DahlS.Z-Lepr(fa)/Lepr(fa) rat

OBJECTIVE: The DahlS.Z-Lepr(fa)/Lepr(fa) (DS/obese) rat strain was established from a cross between Dahl salt-sensitive rats and Zucker fatty (fa/fa) rats, the latter of which harbor a missense mutation in the leptin receptor gene (Lepr). We examined whether DS/obese rats might be a suitable animal...

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Detalles Bibliográficos
Autores principales:	Hattori, T, Murase, T, Ohtake, M, Inoue, T, Tsukamoto, H, Takatsu, M, Kato, Y, Hashimoto, K, Murohara, T, Nagata, K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302131/ https://www.ncbi.nlm.nih.gov/pubmed/23154293 http://dx.doi.org/10.1038/nutd.2010.1

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