Neutrophil depletion impairs natural killer cell maturation, function, and homeostasis

Natural killer (NK) cells are bone marrow (BM)–derived granular lymphocytes involved in immune defense against microbial infections and tumors. In an N-ethyl N-nitrosourea (ENU) mutagenesis strategy, we identified a mouse mutant with impaired NK cell reactivity both in vitro and in vivo. Dissection...

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Detalles Bibliográficos
Autores principales: Jaeger, Baptiste N., Donadieu, Jean, Cognet, Céline, Bernat, Claire, Ordoñez-Rueda, Diana, Barlogis, Vincent, Mahlaoui, Nizar, Fenis, Aurore, Narni-Mancinelli, Emilie, Beaupain, Blandine, Bellanné-Chantelot, Christine, Bajénoff, Marc, Malissen, Bernard, Malissen, Marie, Vivier, Eric, Ugolini, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302230/
https://www.ncbi.nlm.nih.gov/pubmed/22393124
http://dx.doi.org/10.1084/jem.20111908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302230/
https://www.ncbi.nlm.nih.gov/pubmed/22393124
http://dx.doi.org/10.1084/jem.20111908

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