Cargando…

Neutrophil depletion impairs natural killer cell maturation, function, and homeostasis

Natural killer (NK) cells are bone marrow (BM)–derived granular lymphocytes involved in immune defense against microbial infections and tumors. In an N-ethyl N-nitrosourea (ENU) mutagenesis strategy, we identified a mouse mutant with impaired NK cell reactivity both in vitro and in vivo. Dissection...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jaeger, Baptiste N., Donadieu, Jean, Cognet, Céline, Bernat, Claire, Ordoñez-Rueda, Diana, Barlogis, Vincent, Mahlaoui, Nizar, Fenis, Aurore, Narni-Mancinelli, Emilie, Beaupain, Blandine, Bellanné-Chantelot, Christine, Bajénoff, Marc, Malissen, Bernard, Malissen, Marie, Vivier, Eric, Ugolini, Sophie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302230/ https://www.ncbi.nlm.nih.gov/pubmed/22393124 http://dx.doi.org/10.1084/jem.20111908

Ejemplares similares

Congenital neutropenia: diagnosis, molecular bases and patient management
por: Donadieu, Jean, et al.
Publicado: (2011)

Biallelic CXCR2 loss-of-function mutations define a distinct congenital neutropenia entity
por: Marin-Esteban, Viviana, et al.
Publicado: (2021)

Identification of biallelic germline variants of SRP68 in a sporadic case with severe congenital neutropenia
por: Schmaltz-Panneau, Barbara, et al.
Publicado: (2021)

Role of the ITAM-Bearing Receptors Expressed by Natural Killer Cells in Cancer
por: Medjouel Khlifi, Hakim, et al.
Publicado: (2022)

Innate and adaptive immunity: specificities and signaling hierarchies revisited
por: Vivier, Eric, et al.
Publicado: (2004)

Visualizing Early Splenic Memory CD8(+) T Cells Reactivation against Intracellular Bacteria in the Mouse
por: Bajénoff, Marc, et al.
Publicado: (2010)

Establishment of MOS-SF36 percentile ranks in the general youth French population
por: Trognon, Arthur, et al.
Publicado: (2022)

Natural Killer Cells: From Basic Research to Treatments
por: Vivier, Eric, et al.
Publicado: (2011)

T cell regulation of natural killer cells
por: Kerdiles, Yann, et al.
Publicado: (2013)

Description and outcome of a cohort of 8 patients with WHIM syndrome from the French Severe Chronic Neutropenia Registry
por: Beaussant Cohen, Sarah, et al.
Publicado: (2012)

CD8β Increases CD8 Coreceptor Function and Participation in TCR–Ligand Binding
por: Renard, Valery, et al.
Publicado: (1996)

Neutrophils Exert a Suppressive Effect on Th1 Responses to Intracellular Pathogen Brucella abortus
por: Barquero-Calvo, Elías, et al.
Publicado: (2013)

Clinical spectrum and long-term follow-up of 14 cases with G6PC3 mutations from the French severe congenital neutropenia registry
por: Desplantes, Claire, et al.
Publicado: (2014)

HSCT may lower leukemia risk in ELANE neutropenia: a before–after study from the French Severe Congenital Neutropenia Registry
por: Rotulo, Gioacchino Andrea, et al.
Publicado: (2020)

Single-cell profiling reveals the trajectories of natural killer cell differentiation in bone marrow and a stress signature induced by acute myeloid leukemia
por: Crinier, Adeline, et al.
Publicado: (2020)

Best practice guidelines for the molecular genetic diagnosis of maturity-onset diabetes of the young
por: Ellard, S., et al.
Publicado: (2008)

Unveiling skin macrophage dynamics explains both tattoo persistence and strenuous removal
por: Baranska, Anna, et al.
Publicado: (2018)

The CD3-γδε and CD3-ζ/η Modules Are Each Essential for Allelic Exclusion at the T Cell Receptor β Locus but Are Both Dispensable for the Initiation of V to (D)J Recombination at the T Cell Receptor–β, –γ, and –δ Loci
por: Ardouin, Laurence, et al.
Publicado: (1998)

Natural history of GATA2 deficiency in a survey of 79 French and Belgian patients
por: Donadieu, Jean, et al.
Publicado: (2018)

Manufacturing Natural Killer Cells as Medicinal Products
por: Chabannon, Christian, et al.
Publicado: (2016)

The Single Positive T Cells Found in CD3-ζ/η(−) (/−) Mice Overtly React with Self–Major Histocompatibility Complex Molecules upon Restoration of Normal Surface Density of T Cell Receptor–CD3 Complex
por: Lin, Shih-Yao, et al.
Publicado: (1997)

Dominant Role of CD80–CD86 Over CD40 and ICOSL in the Massive Polyclonal B Cell Activation Mediated by LAT(Y136F) CD4(+) T Cells
por: Chevrier, Stéphane, et al.
Publicado: (2012)

FHL2 Regulates Natural Killer Cell Development and Activation during Streptococcus pneumoniae Infection
por: Baranek, Thomas, et al.
Publicado: (2017)

The Common Cytokine Receptor γ Chain Controls Survival of γ/δ T Cells
por: Malissen, Marie, et al.
Publicado: (1997)

Phenotype and Functions of Natural Killer Cells in Critically-Ill Septic Patients
por: Forel, Jean-Marie, et al.
Publicado: (2012)

New somatic BRAF splicing mutation in Langerhans cell histiocytosis
por: Héritier, Sébastien, et al.
Publicado: (2017)

Type 1 Innate Lymphoid Cells Limit the Antitumoral Immune Response
por: Vienne, Margaux, et al.
Publicado: (2021)

Multicolor fate mapping of Langerhans cell homeostasis
por: Ghigo, Clément, et al.
Publicado: (2013)

High-Dimensional Single-Cell Analysis Identifies Organ-Specific Signatures and Conserved NK Cell Subsets in Humans and Mice
por: Crinier, Adeline, et al.
Publicado: (2018)

Evidence of innate lymphoid cell redundancy in humans
por: Vély, Frédéric, et al.
Publicado: (2016)

Natural killer cell-based therapies
por: Romagné, François, et al.
Publicado: (2011)

Bringing natural killer cells to the clinic
por: Chiossone, Laura, et al.
Publicado: (2022)

Genetic Alterations of the Thrombopoietin/MPL/JAK2 Axis Impacting Megakaryopoiesis
por: Plo, Isabelle, et al.
Publicado: (2017)

Identification of MPL R102P Mutation in Hereditary Thrombocytosis
por: Bellanné-Chantelot, Christine, et al.
Publicado: (2017)

Pregnancy in Women With Monogenic Diabetes due to Pathogenic Variants of the Glucokinase Gene: Lessons and Challenges
por: Timsit, José, et al.
Publicado: (2022)

Host resistance to endotoxic shock requires the neuroendocrine regulation of group 1 innate lymphoid cells
por: Quatrini, Linda, et al.
Publicado: (2017)

Long-Term Follow-Up of Oral Glucose Tolerance Test–Derived Glucose Tolerance and Insulin Secretion and Insulin Sensitivity Indexes in Subjects With Glucokinase Mutations (MODY2)
por: Martin, Delphine, et al.
Publicado: (2008)

Severe Congenital Adrenal Hyperplasia Presenting as Bilateral Testicular Tumors and Azoospermia in the Third Decade of Life
por: Sarfati, Julie, et al.
Publicado: (2018)

Mapping the SLP76 interactome in T cells lacking each of the GRB2-family adaptors reveals molecular plasticity of the TCR signaling pathway
por: Ruminski, Kilian, et al.
Publicado: (2023)

The pronounced lung lesions developing in LAT(Y136F) knock-in mice mimic human IgG4-related lung disease
por: Waseda, Yuko, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_oljop9sih8qcu24clpjrgo152o