Dual regulation of IRF4 function in T and B cells is required for the coordination of T–B cell interactions and the prevention of autoimmunity

Effective humoral responses to protein antigens require the precise execution of carefully timed differentiation programs in both T and B cell compartments. Disturbances in this process underlie the pathogenesis of many autoimmune disorders, including systemic lupus erythematosus (SLE). Interferon r...

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Detalles Bibliográficos
Autores principales: Biswas, Partha S., Gupta, Sanjay, Stirzaker, Roslynn A., Kumar, Varsha, Jessberger, Rolf, Lu, Theresa T., Bhagat, Govind, Pernis, Alessandra B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302237/
https://www.ncbi.nlm.nih.gov/pubmed/22370718
http://dx.doi.org/10.1084/jem.20111195

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