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Biosafety Considerations of Mammalian-Transmissible H5N1 Influenza

The ability to produce an H5N1 influenza virus that can be transmitted from human to human raises both biosecurity and biosafety concerns. After analyzing the biosafety risks of such a virus, we propose that it be handled at biosafety level 4 (BSL4) containment until and unless it becomes clear that...

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Detalles Bibliográficos
Autores principales: Imperiale, Michael J., Hanna, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302571/
https://www.ncbi.nlm.nih.gov/pubmed/22396482
http://dx.doi.org/10.1128/mBio.00043-12
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author Imperiale, Michael J.
Hanna, Michael G.
author_facet Imperiale, Michael J.
Hanna, Michael G.
author_sort Imperiale, Michael J.
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description The ability to produce an H5N1 influenza virus that can be transmitted from human to human raises both biosecurity and biosafety concerns. After analyzing the biosafety risks of such a virus, we propose that it be handled at biosafety level 4 (BSL4) containment until and unless it becomes clear that the risks to humans and other mammals can be mitigated.
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spelling pubmed-33025712012-03-15 Biosafety Considerations of Mammalian-Transmissible H5N1 Influenza Imperiale, Michael J. Hanna, Michael G. mBio Commentary The ability to produce an H5N1 influenza virus that can be transmitted from human to human raises both biosecurity and biosafety concerns. After analyzing the biosafety risks of such a virus, we propose that it be handled at biosafety level 4 (BSL4) containment until and unless it becomes clear that the risks to humans and other mammals can be mitigated. American Society of Microbiology 2012-03-06 /pmc/articles/PMC3302571/ /pubmed/22396482 http://dx.doi.org/10.1128/mBio.00043-12 Text en Copyright © 2012 Imperiale and Hanna. http://creativecommons.org/licenses/by-nc-sa/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License (http://creativecommons.org/licenses/by-nc-sa/3.0/) , which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Commentary
Imperiale, Michael J.
Hanna, Michael G.
Biosafety Considerations of Mammalian-Transmissible H5N1 Influenza
title Biosafety Considerations of Mammalian-Transmissible H5N1 Influenza
title_full Biosafety Considerations of Mammalian-Transmissible H5N1 Influenza
title_fullStr Biosafety Considerations of Mammalian-Transmissible H5N1 Influenza
title_full_unstemmed Biosafety Considerations of Mammalian-Transmissible H5N1 Influenza
title_short Biosafety Considerations of Mammalian-Transmissible H5N1 Influenza
title_sort biosafety considerations of mammalian-transmissible h5n1 influenza
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302571/
https://www.ncbi.nlm.nih.gov/pubmed/22396482
http://dx.doi.org/10.1128/mBio.00043-12
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