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PARalyzer: definition of RNA binding sites from PAR-CLIP short-read sequence data
Crosslinking and immunoprecipitation (CLIP) protocols have made it possible to identify transcriptome-wide RNA-protein interaction sites. In particular, PAR-CLIP utilizes a photoactivatable nucleoside for more efficient crosslinking. We present an approach, centered on the novel PARalyzer tool, for...
Autores principales: | Corcoran, David L, Georgiev, Stoyan, Mukherjee, Neelanjan, Gottwein, Eva, Skalsky, Rebecca L, Keene, Jack D, Ohler, Uwe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302668/ https://www.ncbi.nlm.nih.gov/pubmed/21851591 http://dx.doi.org/10.1186/gb-2011-12-8-r79 |
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