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Topiramate Treatment Is Neuroprotective and Reduces Oligodendrocyte Loss after Cervical Spinal Cord Injury

Excess glutamate release and associated neurotoxicity contributes to cell death after spinal cord injury (SCI). Indeed, delayed administration of glutamate receptor antagonists after SCI in rodents improves tissue sparing and functional recovery. Despite their therapeutic potential, most glutamate r...

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Detalles Bibliográficos
Autores principales: Gensel, John C., Tovar, C. Amy, Bresnahan, Jacqueline C., Beattie, Micheal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302770/
https://www.ncbi.nlm.nih.gov/pubmed/22428066
http://dx.doi.org/10.1371/journal.pone.0033519