In Vivo Manganese Exposure Modulates Erk, Akt and Darpp-32 in the Striatum of Developing Rats, and Impairs Their Motor Function

Manganese (Mn) is an essential metal for development and metabolism. However, exposures to high Mn levels may be toxic, especially to the central nervous system (CNS). Neurotoxicity is commonly due to occupational or environmental exposures leading to Mn accumulation in the basal ganglia and a Parki...

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Detalles Bibliográficos
Autores principales: Cordova, Fabiano M., Aguiar, Aderbal S., Peres, Tanara V., Lopes, Mark W., Gonçalves, Filipe M., Remor, Aline P., Lopes, Samantha C., Pilati, Célso, Latini, Alexandra S., Prediger, Rui D. S., Erikson, Keith M., Aschner, Michael, Leal, Rodrigo B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302787/
https://www.ncbi.nlm.nih.gov/pubmed/22427945
http://dx.doi.org/10.1371/journal.pone.0033057

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