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Combinatorial Activation and Repression by Seven Transcription Factors Specify Drosophila Odorant Receptor Expression

The mechanism that specifies olfactory sensory neurons to express only one odorant receptor (OR) from a large repertoire is critical for odor discrimination but poorly understood. Here, we describe the first comprehensive analysis of OR expression regulation in Drosophila. A systematic, RNAi-mediate...

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Detalles Bibliográficos
Autores principales: Jafari, Shadi, Alkhori, Liza, Schleiffer, Alexander, Brochtrup, Anna, Hummel, Thomas, Alenius, Mattias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302810/
https://www.ncbi.nlm.nih.gov/pubmed/22427741
http://dx.doi.org/10.1371/journal.pbio.1001280