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Knockdown of SF-1 and RNF31 Affects Components of Steroidogenesis, TGFβ, and Wnt/β-catenin Signaling in Adrenocortical Carcinoma Cells

The orphan nuclear receptor Steroidogenic Factor-1 (SF-1, NR5A1) is a critical regulator of development and homeostasis of the adrenal cortex and gonads. We recently showed that a complex containing E3 ubiquitin ligase RNF31 and the known SF-1 corepressor DAX-1 (NR0B1) interacts with SF-1 on target...

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Detalles Bibliográficos
Autores principales:	Ehrlund, Anna, Jonsson, Philip, Vedin, Lise-Lotte, Williams, Cecilia, Gustafsson, Jan-Åke, Treuter, Eckardt
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302881/ https://www.ncbi.nlm.nih.gov/pubmed/22427816 http://dx.doi.org/10.1371/journal.pone.0032080

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