Cargando…

Pre-Clinical Evaluation of a (213)Bi-Labeled 2556 Antibody to HIV-1 gp41 Glycoprotein in HIV-1 Mouse Models as a Reagent for HIV Eradication

BACKGROUND: Any strategy for curing HIV infection must include a method to eliminate viral-infected cells. Based on our earlier proof-of-principle results targeting HIV-1 infected cells with radiolabeled antibody (mAb) to gp41 viral antigen, we embarked on identifying a suitable candidate mAb for pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dadachova, Ekaterina, Kitchen, Scott G., Bristol, Gregory, Baldwin, Gayle Cocita, Revskaya, Ekaterina, Empig, Cyril, Thornton, George B., Gorny, Miroslaw K., Zolla-Pazner, Susan, Casadevall, Arturo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302885/ https://www.ncbi.nlm.nih.gov/pubmed/22427811 http://dx.doi.org/10.1371/journal.pone.0031866

Ejemplares similares

Correction: Pre-Clinical Evaluation of a (213)Bi-Labeled 2556 Antibody to HIV-1 gp41 Glycoprotein in HIV-1 Mouse Models as a Reagent for HIV Eradication
por: Dadachova, Ekaterina, et al.
Publicado: (2012)

Immunoprophylaxis against Mother-to-Child Transmission of HIV-1
por: Gorny, Miroslaw K, et al.
Publicado: (2006)

Combination of Antiretroviral Drugs and Radioimmunotherapy Specifically Kills Infected Cells from HIV-Infected Individuals
por: Tsukrov, Dina, et al.
Publicado: (2016)

Targeted Killing of Virally Infected Cells by Radiolabeled Antibodies to Viral Proteins
por: Dadachova, Ekaterina, et al.
Publicado: (2006)

Residue 315 regulates V3 exposure and V3 antibody recognition on HIV subtype B and C viruses
por: Manhas, S, et al.
Publicado: (2012)

Distinct conformational states of HIV-1 gp41 are recognized by neutralizing and non-neutralizing antibodies
por: Frey, Gary, et al.
Publicado: (2010)

Identifying epitopes of HIV-1 that induce protective antibodies
por: Zolla-Pazner, Susan
Publicado: (2004)

Different Pattern of Immunoglobulin Gene Usage by HIV-1 Compared to Non-HIV-1 Antibodies Derived from the Same Infected Subject
por: Li, Liuzhe, et al.
Publicado: (2012)

Anti-V3 Monoclonal Antibodies Display Broad Neutralizing Activities against Multiple HIV-1 Subtypes
por: Hioe, Catarina E., et al.
Publicado: (2010)

Treating Cancer as an Infectious Disease—Viral Antigens as Novel Targets for Treatment and Potential Prevention of Tumors of Viral Etiology
por: Wang, Xing Guo, et al.
Publicado: (2007)

2556. Does a Brief Education Intervention Affect Perceptions and Knowledge Regarding HIV Pre-Exposure Prophylaxis Among Medical Trainees?
por: Myers, Michaela, et al.
Publicado: (2019)

Comparative Magnitude of Cross-Strain Conservation of HIV Variable Loop Neutralization Epitopes
por: Swetnam, James, et al.
Publicado: (2010)

Transcriptional Profiling of Mycobacterium tuberculosis Replicating Ex vivo in Blood from HIV- and HIV+ Subjects
por: Ryndak, Michelle B., et al.
Publicado: (2014)

Beta emitters rhenium‐188 and lutetium‐177 are equally effective in radioimmunotherapy of HPV‐positive experimental cervical cancer
por: Phaeton, Rebecca, et al.
Publicado: (2015)

P12-13. Structure-guided design and immunological characterization of immunogen constructs presenting the HIV-1 gp120 V3 loop on a CTB scaffold
por: Totrov, M, et al.
Publicado: (2009)

Resistance of Subtype C HIV-1 Strains to Anti-V3 Loop Antibodies
por: Almond, David, et al.
Publicado: (2012)

Cryptococcus neoformans as a Model for Radioimmunotherapy of Infections
por: Dadachova, Ekaterina, et al.
Publicado: (2011)

Impact of IgG Isotype on the Induction of Antibody-Dependent Cellular Phagocytosis of HIV by Human Milk Leukocytes
por: Fox, Alisa, et al.
Publicado: (2022)

Indirect Detection of an Epitope-Specific Response to HIV-1 gp120 Immunization in Human Subjects
por: Shmelkov, Evgeny, et al.
Publicado: (2011)

Vaccine-induced V1V2-specific antibodies control and or protect against infection with HIV, SIV and SHIV
por: Zolla-Pazner, Susan, et al.
Publicado: (2019)

Search for antiviral functions of potentially protective antibodies against V2 region of HIV-1
por: Gorny, Miroslaw K.
Publicado: (2020)

Antibody Recognition of CD4-Induced Open HIV-1 Env Trimers
por: Yang, Zhi, et al.
Publicado: (2022)

Optimized protocol for detection of native, full‐length HIV‐1 envelope on the surface of transfected cells
por: Altman, J.B., et al.
Publicado: (2018)

Alterations of HIV-1 envelope phenotype and antibody-mediated neutralization by signal peptide mutations
por: Upadhyay, Chitra, et al.
Publicado: (2018)

Human Anti-V3 HIV-1 Monoclonal Antibodies Encoded by the VH5-51/VL Lambda Genes Define a Conserved Antigenic Structure
por: Gorny, Miroslaw K., et al.
Publicado: (2011)

Casp8p41 and HIV
por: Cummins, Nathan W., et al.
Publicado: (2015)

gp41: HIV's shy protein
por: Zwick, Michael B, et al.
Publicado: (2004)

Monoclonal antibody-based therapies for microbial diseases
por: Saylor, Carolyn, et al.
Publicado: (2009)

P19-21. Sequence variability in the crown of the V3 loop of the HIV-1 envelope is clustered within a small 3D structural zone
por: Almond, D, et al.
Publicado: (2009)

Focusing the immune response on the V3 loop of HIV-1 gp120 induces cross-clade neutralizing
por: Zolla-Pazner, Susan, et al.
Publicado: (2006)

PB2556: MEGALOBLASTIC ANEMIA: EPIDEMIOLOGICAL, CLINICAL, AND ETIOLOGICAL PROFILE: ABOUT 200 CASES.
por: Zahra, Kmira, et al.
Publicado: (2023)

Comparative Radioimmunotherapy of Experimental Melanoma with Novel Humanized Antibody to Melanin Labeled with 213Bismuth and 177Lutetium
por: Allen, Kevin J. H., et al.
Publicado: (2019)

Epitope Mapping of Conformational V2-specific Anti-HIV Human Monoclonal Antibodies Reveals an Immunodominant Site in V2
por: Mayr, Luzia M., et al.
Publicado: (2013)

V2-Specific Antibodies in HIV-1 Vaccine Research and Natural Infection: Controllers or Surrogate Markers
por: Duerr, Ralf, et al.
Publicado: (2019)

P04-55 LB. Anti-V3 monoclonal antibodies display broad neutralizing activities against multiple HIV-1 subtypes
por: Zolla-Pazner, S, et al.
Publicado: (2009)

Association of Diverse Genotypes and Phenotypes of Immune Cells and Immunoglobulins With the Course of HIV-1 Infection
por: Li, Liuzhe, et al.
Publicado: (2018)

P04-42. Molecular design of a mimotope that preserves conserved structural elements of the HIV-1 V3 crown
por: Jiang, X, et al.
Publicado: (2009)

High-resolution crystal structure of the Fv of quaternary neutralizing epitope mAb 2909 reveals atomic details of its antigen-binding site
por: Sampson, JM, et al.
Publicado: (2012)

Longitudinal Study of Primary HIV-1 Isolates in Drug-Naïve Individuals Reveals the Emergence of Variants Sensitive to Anti-HIV-1 Monoclonal Antibodies
por: Haldar, Bijayesh, et al.
Publicado: (2011)

Neutralizing Antibodies Targeting HIV-1 gp41
por: Caillat, Christophe, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_popuju9alugqku8la7r9antqvv