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Small-Animal PET Imaging of Amyloid-Beta Plaques with [(11)C]PiB and Its Multi-Modal Validation in an APP/PS1 Mouse Model of Alzheimer's Disease

In vivo imaging and quantification of amyloid-β plaque (Aβ) burden in small-animal models of Alzheimer's disease (AD) is a valuable tool for translational research such as developing specific imaging markers and monitoring new therapy approaches. Methodological constraints such as image resolut...

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Detalles Bibliográficos
Autores principales:	Manook, André, Yousefi, Behrooz H., Willuweit, Antje, Platzer, Stefan, Reder, Sybille, Voss, Andreas, Huisman, Marc, Settles, Markus, Neff, Frauke, Velden, Joachim, Schoor, Michael, von der Kammer, Heinz, Wester, Hans-Jürgen, Schwaiger, Markus, Henriksen, Gjermund, Drzezga, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302888/ https://www.ncbi.nlm.nih.gov/pubmed/22427802 http://dx.doi.org/10.1371/journal.pone.0031310

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