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Atomistic basis for the on–off signaling mechanism in SAM-II riboswitch
Many bacterial genes are controlled by metabolite sensing motifs known as riboswitches, normally located in the 5′ un-translated region of their mRNAs. Small molecular metabolites bind to the aptamer domain of riboswitches with amazing specificity, modulating gene regulation in a feedback loop as a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303485/ https://www.ncbi.nlm.nih.gov/pubmed/19969538 http://dx.doi.org/10.1093/nar/gkp1106 |