From Murine to Human Nude/SCID: The Thymus, T-Cell Development and the Missing Link

Primary immunodeficiencies (PIDs) are disorders of the immune system, which lead to increased susceptibility to infections. T-cell defects, which may affect T-cell development/function, are approximately 11% of reported PIDs. The pathogenic mechanisms are related to molecular alterations not only of...

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Detalles Bibliográficos
Autores principales: Romano, Rosa, Palamaro, Loredana, Fusco, Anna, Iannace, Leucio, Maio, Stefano, Vigliano, Ilaria, Giardino, Giuliana, Pignata, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303720/
https://www.ncbi.nlm.nih.gov/pubmed/22474479
http://dx.doi.org/10.1155/2012/467101

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