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Evaluating our ability to predict the structural disruption of RNA by SNPs

The structure of RiboNucleic Acid (RNA) has the potential to be altered by a Single Nucleotide Polymorphism (SNP). Disease-associated SNPs mapping to non-coding regions of the genome that are transcribed into RiboNucleic Acid (RNA) can potentially affect cellular regulation (and cause disease) by al...

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Detalles Bibliográficos
Autores principales: Ritz, Justin, Martin, Joshua S, Laederach, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303743/
https://www.ncbi.nlm.nih.gov/pubmed/22759654
http://dx.doi.org/10.1186/1471-2164-13-S4-S6

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