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Evaluating our ability to predict the structural disruption of RNA by SNPs
The structure of RiboNucleic Acid (RNA) has the potential to be altered by a Single Nucleotide Polymorphism (SNP). Disease-associated SNPs mapping to non-coding regions of the genome that are transcribed into RiboNucleic Acid (RNA) can potentially affect cellular regulation (and cause disease) by al...
Autores principales: | Ritz, Justin, Martin, Joshua S, Laederach, Alain |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303743/ https://www.ncbi.nlm.nih.gov/pubmed/22759654 http://dx.doi.org/10.1186/1471-2164-13-S4-S6 |
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