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Inhibition of Intestinal Adenoma Formation in APC(Min/) (+) Mice by Riccardin D, a Natural Product Derived from Liverwort Plant Dumortiera hirsuta
BACKGROUND: Mutation of tumor suppressor gene, adenomatous polyposis coli (APC), is the primary molecular event in the development of most intestinal carcinomas. Animal model with APC gene mutation is an effective tool for study of preventive approaches against intestinal carcinomas. We aimed to eva...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303813/ https://www.ncbi.nlm.nih.gov/pubmed/22432006 http://dx.doi.org/10.1371/journal.pone.0033243 |