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Intraperitoneal but Not Intravenous Cryopreserved Mesenchymal Stromal Cells Home to the Inflamed Colon and Ameliorate Experimental Colitis

BACKGROUND AND AIMS: Mesenchymal stromal cells (MSCs) were shown to have immunomodulatory activity and have been applied for treating immune-mediated disorders. We compared the homing and therapeutic action of cryopreserved subcutaneous adipose tissue (AT-MSCs) and bone marrow-derived mesenchymal st...

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Detalles Bibliográficos
Autores principales: Castelo-Branco, Morgana T. L., Soares, Igor D. P., Lopes, Daiana V., Buongusto, Fernanda, Martinusso, Cesonia A., do Rosario, Alyson, Souza, Sergio A. L., Gutfilen, Bianca, Fonseca, Lea Mirian B., Elia, Celeste, Madi, Kalil, Schanaider, Alberto, Rossi, Maria Isabel D., Souza, Heitor S. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303821/
https://www.ncbi.nlm.nih.gov/pubmed/22432015
http://dx.doi.org/10.1371/journal.pone.0033360