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Impact of Preexisting Adenovirus Vector Immunity on Immunogenicity and Protection Conferred with an Adenovirus-Based H5N1 Influenza Vaccine

The prevalence of preexisting immunity to adenoviruses in the majority of the human population might adversely impact the development of adaptive immune responses against adenovirus vector-based vaccines. To address this issue, we primed BALB/c mice either intranasally (i.n.) or intramuscularly (i.m...

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Detalles Bibliográficos
Autores principales:	Pandey, Aseem, Singh, Neetu, Vemula, Sai V., Couëtil, Laurent, Katz, Jacqueline M., Donis, Ruben, Sambhara, Suryaprakash, Mittal, Suresh K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303828/ https://www.ncbi.nlm.nih.gov/pubmed/22432020 http://dx.doi.org/10.1371/journal.pone.0033428

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