A Genome-Wide RNAi Screen Identifies Regulators of Cholesterol-Modified Hedgehog Secretion in Drosophila

Hedgehog (Hh) proteins are secreted molecules that function as organizers in animal development. In addition to being palmitoylated, Hh is the only metazoan protein known to possess a covalently-linked cholesterol moiety. The absence of either modification severely disrupts the organization of numer...

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Detalles Bibliográficos
Autores principales: Aikin, Reid, Cervantes, Alexandra, D'Angelo, Gisela, Ruel, Laurent, Lacas-Gervais, Sandra, Schaub, Sébastien, Thérond, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303847/
https://www.ncbi.nlm.nih.gov/pubmed/22432040
http://dx.doi.org/10.1371/journal.pone.0033665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303847/
https://www.ncbi.nlm.nih.gov/pubmed/22432040
http://dx.doi.org/10.1371/journal.pone.0033665

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