Small Interference RNA Targeting TLR4 Gene Effectively Attenuates Pulmonary Inflammation in a Rat Model

Objective. The present study was to investigate the feasibility of adenovirus-mediated small interference RNA (siRNA) targeting Toll-like receptor 4 (TLR4) gene in ameliorating lipopolysaccharide- (LPS-) induced acute lung injury (ALI). Methods. In vitro, alveolar macrophages (AMs) were treated with...

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Detalles Bibliográficos
Autores principales: Wu, Feixiang, Liu, Yantao, Lv, Xin, Miao, Xuerong, Sun, Yuming, Yu, Weifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303866/
https://www.ncbi.nlm.nih.gov/pubmed/22496605
http://dx.doi.org/10.1155/2012/406435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303866/
https://www.ncbi.nlm.nih.gov/pubmed/22496605
http://dx.doi.org/10.1155/2012/406435

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