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Targeting Costimulatory Molecules to Improve Antitumor Immunity

The full activation of T cells necessitates the concomitant activation of two signals, the engagement of T-cell receptor by peptide/major histocompatibility complex II and an additional signal delivered by costimulatory molecules. The best characterized costimulatory molecules belong to B7/CD28 and...

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Detalles Bibliográficos
Autores principales: Capece, Daria, Verzella, Daniela, Fischietti, Mariafausta, Zazzeroni, Francesca, Alesse, Edoardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303883/
https://www.ncbi.nlm.nih.gov/pubmed/22500111
http://dx.doi.org/10.1155/2012/926321

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