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Cytokine receptor modulation by interleukin-2 broadly regulates T helper cell lineage differentiation

T helper (T(H)) cells control host-defense to pathogens. The receptors for IL-12, IL-4, and IL-6 are required for T(H)1, T(H)2, and T(H)17 differentiation, respectively. IL-2 signaling via the transcription factor STAT5 controls T(H)2 differentiation by regulating the T(H)2 cytokine gene cluster and...

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Detalles Bibliográficos
Autores principales:	Liao, Wei, Lin, Jian-Xin, Wang, Lu, Li, Peng, Leonard, Warren J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304099/ https://www.ncbi.nlm.nih.gov/pubmed/21516110 http://dx.doi.org/10.1038/ni.2030

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