Biomarker Discovery by Novel Sensors Based on Nanoproteomics Approaches

During the last years, proteomics has facilitated biomarker discovery by coupling high-throughput techniques with novel nanosensors. In the present review, we focus on the study of label-based and label-free detection systems, as well as nanotechnology approaches, indicating their advantages and app...

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Detalles Bibliográficos
Autores principales: Dasilva, Noelia, Díez, Paula, Matarraz, Sergio, González-González, María, Paradinas, Sara, Orfao, Alberto, Fuentes, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304166/
https://www.ncbi.nlm.nih.gov/pubmed/22438764
http://dx.doi.org/10.3390/s120202284
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author Dasilva, Noelia
Díez, Paula
Matarraz, Sergio
González-González, María
Paradinas, Sara
Orfao, Alberto
Fuentes, Manuel
author_facet Dasilva, Noelia
Díez, Paula
Matarraz, Sergio
González-González, María
Paradinas, Sara
Orfao, Alberto
Fuentes, Manuel
author_sort Dasilva, Noelia
collection PubMed
description During the last years, proteomics has facilitated biomarker discovery by coupling high-throughput techniques with novel nanosensors. In the present review, we focus on the study of label-based and label-free detection systems, as well as nanotechnology approaches, indicating their advantages and applications in biomarker discovery. In addition, several disease biomarkers are shown in order to display the clinical importance of the improvement of sensitivity and selectivity by using nanoproteomics approaches as novel sensors.
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spelling pubmed-33041662012-03-21 Biomarker Discovery by Novel Sensors Based on Nanoproteomics Approaches Dasilva, Noelia Díez, Paula Matarraz, Sergio González-González, María Paradinas, Sara Orfao, Alberto Fuentes, Manuel Sensors (Basel) Review During the last years, proteomics has facilitated biomarker discovery by coupling high-throughput techniques with novel nanosensors. In the present review, we focus on the study of label-based and label-free detection systems, as well as nanotechnology approaches, indicating their advantages and applications in biomarker discovery. In addition, several disease biomarkers are shown in order to display the clinical importance of the improvement of sensitivity and selectivity by using nanoproteomics approaches as novel sensors. Molecular Diversity Preservation International (MDPI) 2012-02-16 /pmc/articles/PMC3304166/ /pubmed/22438764 http://dx.doi.org/10.3390/s120202284 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Dasilva, Noelia
Díez, Paula
Matarraz, Sergio
González-González, María
Paradinas, Sara
Orfao, Alberto
Fuentes, Manuel
Biomarker Discovery by Novel Sensors Based on Nanoproteomics Approaches
title Biomarker Discovery by Novel Sensors Based on Nanoproteomics Approaches
title_full Biomarker Discovery by Novel Sensors Based on Nanoproteomics Approaches
title_fullStr Biomarker Discovery by Novel Sensors Based on Nanoproteomics Approaches
title_full_unstemmed Biomarker Discovery by Novel Sensors Based on Nanoproteomics Approaches
title_short Biomarker Discovery by Novel Sensors Based on Nanoproteomics Approaches
title_sort biomarker discovery by novel sensors based on nanoproteomics approaches
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304166/
https://www.ncbi.nlm.nih.gov/pubmed/22438764
http://dx.doi.org/10.3390/s120202284
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AT orfaoalberto biomarkerdiscoverybynovelsensorsbasedonnanoproteomicsapproaches
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