BRCA1 testing should be offered to individuals with triple-negative breast cancer diagnosed below 50 years

BACKGROUND: Triple-negative (TN) tumours are the predominant breast cancer subtype in BRCA1 mutation carriers. Recently, it was proposed that all individuals below 50 years of age with TN breast cancer should be offered BRCA testing. We have evaluated the BRCA1 mutation frequency and the implication...

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Detalles Bibliográficos
Autores principales: Robertson, L, Hanson, H, Seal, S, Warren-Perry, M, Hughes, D, Howell, I, Turnbull, C, Houlston, R, Shanley, S, Butler, S, Evans, D G, Ross, G, Eccles, D, Tutt, A, Rahman, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304410/
https://www.ncbi.nlm.nih.gov/pubmed/22333603
http://dx.doi.org/10.1038/bjc.2012.31

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