Prognostic significance of chromosome 3 alterations determined by microsatellite analysis in uveal melanoma: a long-term follow-up study

BACKGROUND: In uveal melanoma (UM), the most frequent primary intraocular tumour in adults, loss of one entire chromosome 3 (monosomy 3 (M3)) is observed in ∼50% of tumours and is significantly associated with metastatic disease. The strong association of metastatic disease with M3 offers the opport...

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Detalles Bibliográficos
Autores principales: Thomas, S, Pütter, C, Weber, S, Bornfeld, N, Lohmann, D R, Zeschnigk, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304422/
https://www.ncbi.nlm.nih.gov/pubmed/22353812
http://dx.doi.org/10.1038/bjc.2012.54

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304422/
https://www.ncbi.nlm.nih.gov/pubmed/22353812
http://dx.doi.org/10.1038/bjc.2012.54

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