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Prognostic significance of chromosome 3 alterations determined by microsatellite analysis in uveal melanoma: a long-term follow-up study
BACKGROUND: In uveal melanoma (UM), the most frequent primary intraocular tumour in adults, loss of one entire chromosome 3 (monosomy 3 (M3)) is observed in ∼50% of tumours and is significantly associated with metastatic disease. The strong association of metastatic disease with M3 offers the opport...
Autores principales: | Thomas, S, Pütter, C, Weber, S, Bornfeld, N, Lohmann, D R, Zeschnigk, M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304422/ https://www.ncbi.nlm.nih.gov/pubmed/22353812 http://dx.doi.org/10.1038/bjc.2012.54 |
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