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Phenformin as prophylaxis and therapy in breast cancer xenografts

BACKGROUND: Observations that diabetics treated with biguanide drugs have a reduced risk of developing cancer have prompted an enthusiasm for these agents as anti-cancer therapies. We sought to determine the efficacy of the biguanide phenformin in the chemoprophylaxis and in the treatment of oestrog...

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Detalles Bibliográficos
Autores principales:	Appleyard, M V C L, Murray, K E, Coates, P J, Wullschleger, S, Bray, S E, Kernohan, N M, Fleming, S, Alessi, D R, Thompson, A M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304424/ https://www.ncbi.nlm.nih.gov/pubmed/22361631 http://dx.doi.org/10.1038/bjc.2012.56

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