Effects of the knockdown of hypoxia inducible factor-1α expression by adenovirus-mediated shRNA on angiogenesis and tumor growth in hepatocellular carcinoma cell lines

BACKGROUND/AIMS: Hypoxia-inducible factor-1α (HIF-1α) is a central transcriptional factor involved in the cellular responses related to various aspects of cancer biology, including proliferation, survival, and angiogenesis, and the metabolism of the extracellular matrix in hypoxia. This study evalua...

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Detalles Bibliográficos
Autores principales: Choi, Sung Hoon, Shin, Hye Won, Park, Jun Yong, Yoo, Ji Young, Kim, Do Young, Ro, Weon Sang, Yun, Chae-Ok, Han, Kwang-Hyub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association for the Study of the Liver 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304594/
https://www.ncbi.nlm.nih.gov/pubmed/20924210
http://dx.doi.org/10.3350/kjhep.2010.16.3.280

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