A case of amoxicillin-induced hepatocellular liver injury with bile-duct damage

Amoxicillin, an antibiotic that is widely prescribed for various infections, is associated with a very low rate of drug-induced liver injury; hepatitis and cholestasis are rare complications. Here we present a case of a 39-year-old woman who was diagnosed with abdominal actinomycosis and received am...

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Detalles Bibliográficos
Autores principales: Kim, Ju Seung, Jang, Young Rock, Lee, Ji Won, Kim, Jin Yong, Jung, Young Kul, Chung, Dong Hae, Kwon, Oh Sang, Kim, Yun Soo, Choi, Duck Joo, Kim, Ju Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association for the Study of the Liver 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304646/
https://www.ncbi.nlm.nih.gov/pubmed/22102391
http://dx.doi.org/10.3350/kjhep.2011.17.3.229
Descripción
Sumario:Amoxicillin, an antibiotic that is widely prescribed for various infections, is associated with a very low rate of drug-induced liver injury; hepatitis and cholestasis are rare complications. Here we present a case of a 39-year-old woman who was diagnosed with abdominal actinomycosis and received amoxicillin treatment. The patient displayed hepatocellular and bile-duct injury, in addition to elevated levels of liver enzymes. The patient was diagnosed with amoxicillin-induced cholestatic hepatitis. When amoxicillin was discontinued, the patient's symptoms improved and her liver enzyme levels reduced to near to the normal range.

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