A case of amoxicillin-induced hepatocellular liver injury with bile-duct damage

Amoxicillin, an antibiotic that is widely prescribed for various infections, is associated with a very low rate of drug-induced liver injury; hepatitis and cholestasis are rare complications. Here we present a case of a 39-year-old woman who was diagnosed with abdominal actinomycosis and received am...

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Autores principales: Kim, Ju Seung, Jang, Young Rock, Lee, Ji Won, Kim, Jin Yong, Jung, Young Kul, Chung, Dong Hae, Kwon, Oh Sang, Kim, Yun Soo, Choi, Duck Joo, Kim, Ju Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association for the Study of the Liver 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304646/
https://www.ncbi.nlm.nih.gov/pubmed/22102391
http://dx.doi.org/10.3350/kjhep.2011.17.3.229
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author Kim, Ju Seung
Jang, Young Rock
Lee, Ji Won
Kim, Jin Yong
Jung, Young Kul
Chung, Dong Hae
Kwon, Oh Sang
Kim, Yun Soo
Choi, Duck Joo
Kim, Ju Hyun
author_facet Kim, Ju Seung
Jang, Young Rock
Lee, Ji Won
Kim, Jin Yong
Jung, Young Kul
Chung, Dong Hae
Kwon, Oh Sang
Kim, Yun Soo
Choi, Duck Joo
Kim, Ju Hyun
author_sort Kim, Ju Seung
collection PubMed
description Amoxicillin, an antibiotic that is widely prescribed for various infections, is associated with a very low rate of drug-induced liver injury; hepatitis and cholestasis are rare complications. Here we present a case of a 39-year-old woman who was diagnosed with abdominal actinomycosis and received amoxicillin treatment. The patient displayed hepatocellular and bile-duct injury, in addition to elevated levels of liver enzymes. The patient was diagnosed with amoxicillin-induced cholestatic hepatitis. When amoxicillin was discontinued, the patient's symptoms improved and her liver enzyme levels reduced to near to the normal range.
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spelling pubmed-33046462012-03-20 A case of amoxicillin-induced hepatocellular liver injury with bile-duct damage Kim, Ju Seung Jang, Young Rock Lee, Ji Won Kim, Jin Yong Jung, Young Kul Chung, Dong Hae Kwon, Oh Sang Kim, Yun Soo Choi, Duck Joo Kim, Ju Hyun Korean J Hepatol Case Report Amoxicillin, an antibiotic that is widely prescribed for various infections, is associated with a very low rate of drug-induced liver injury; hepatitis and cholestasis are rare complications. Here we present a case of a 39-year-old woman who was diagnosed with abdominal actinomycosis and received amoxicillin treatment. The patient displayed hepatocellular and bile-duct injury, in addition to elevated levels of liver enzymes. The patient was diagnosed with amoxicillin-induced cholestatic hepatitis. When amoxicillin was discontinued, the patient's symptoms improved and her liver enzyme levels reduced to near to the normal range. The Korean Association for the Study of the Liver 2011-09 2011-09-30 /pmc/articles/PMC3304646/ /pubmed/22102391 http://dx.doi.org/10.3350/kjhep.2011.17.3.229 Text en Copyright © 2011 by The Korean Association for the Study of the Liver http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kim, Ju Seung
Jang, Young Rock
Lee, Ji Won
Kim, Jin Yong
Jung, Young Kul
Chung, Dong Hae
Kwon, Oh Sang
Kim, Yun Soo
Choi, Duck Joo
Kim, Ju Hyun
A case of amoxicillin-induced hepatocellular liver injury with bile-duct damage
title A case of amoxicillin-induced hepatocellular liver injury with bile-duct damage
title_full A case of amoxicillin-induced hepatocellular liver injury with bile-duct damage
title_fullStr A case of amoxicillin-induced hepatocellular liver injury with bile-duct damage
title_full_unstemmed A case of amoxicillin-induced hepatocellular liver injury with bile-duct damage
title_short A case of amoxicillin-induced hepatocellular liver injury with bile-duct damage
title_sort case of amoxicillin-induced hepatocellular liver injury with bile-duct damage
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304646/
https://www.ncbi.nlm.nih.gov/pubmed/22102391
http://dx.doi.org/10.3350/kjhep.2011.17.3.229
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