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Mutations in Polymerase Genes Enhanced the Virulence of 2009 Pandemic H1N1 Influenza Virus in Mice

Influenza A virus can infect a wide variety of animal species with illness ranging from mild to severe, and is a continual cause for concern. Genetic mutations that occur either naturally or during viral adaptation in a poorly susceptible host are key mechanisms underlying the evolution and virulenc...

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Detalles Bibliográficos
Autores principales:	Zhu, Wenfei, Zhu, Yun, Qin, Kun, Yu, Zaijiang, Gao, Rongbao, Yu, Huiyan, Zhou, Jianfang, Shu, Yuelong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305307/ https://www.ncbi.nlm.nih.gov/pubmed/22438920 http://dx.doi.org/10.1371/journal.pone.0033383

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