Heat-Shock Mediated Overexpression of HNF1β Mutations Has Differential Effects on Gene Expression in the Xenopus Pronephric Kidney

The transcription factor HNF1B, encoded by the TCF2 gene, plays an important role in the organogenesis of vertebrates. In humans, heterozygous mutations of HNF1B are associated with several diseases, such as pancreatic β-cell dysfunction leading to maturity-onset diabetes of the young (MODY5), defec...

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Detalles Bibliográficos
Autores principales: Sauert, Kathrin, Kahnert, Stefan, Roose, Magdalena, Gull, Mazhar, Brändli, André W., Ryffel, Gerhart U., Waldner, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305329/
https://www.ncbi.nlm.nih.gov/pubmed/22438943
http://dx.doi.org/10.1371/journal.pone.0033522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305329/
https://www.ncbi.nlm.nih.gov/pubmed/22438943
http://dx.doi.org/10.1371/journal.pone.0033522

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