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Conformational Control of the Binding of the Transactivation Domain of the MLL Protein and c-Myb to the KIX Domain of CREB

The KIX domain of CBP is a transcriptional coactivator. Concomitant binding to the activation domain of proto-oncogene protein c-Myb and the transactivation domain of the trithorax group protein mixed lineage leukemia (MLL) transcription factor lead to the biologically active ternary MLL∶KIX∶c-Myb c...

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Detalles Bibliográficos
Autores principales:	Korkmaz, Elif Nihal, Nussinov, Ruth, Haliloğlu, Türkan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305381/ https://www.ncbi.nlm.nih.gov/pubmed/22438798 http://dx.doi.org/10.1371/journal.pcbi.1002420

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