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Temporal Transcriptional Profiling of Somatic and Germ Cells Reveals Biased Lineage Priming of Sexual Fate in the Fetal Mouse Gonad
The divergence of distinct cell populations from multipotent progenitors is poorly understood, particularly in vivo. The gonad is an ideal place to study this process, because it originates as a bipotential primordium where multiple distinct lineages acquire sex-specific fates as the organ different...
Autores principales: | Jameson, Samantha A., Natarajan, Anirudh, Cool, Jonah, DeFalco, Tony, Maatouk, Danielle M., Mork, Lindsey, Munger, Steven C., Capel, Blanche |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305395/ https://www.ncbi.nlm.nih.gov/pubmed/22438826 http://dx.doi.org/10.1371/journal.pgen.1002575 |
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