Cargando…

A Splice Site Variant in the Bovine RNF11 Gene Compromises Growth and Regulation of the Inflammatory Response

We report association mapping of a locus on bovine chromosome 3 that underlies a Mendelian form of stunted growth in Belgian Blue Cattle (BBC). By resequencing positional candidates, we identify the causative c124-2A>G splice variant in intron 1 of the RNF11 gene, for which all affected animals a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sartelet, Arnaud, Druet, Tom, Michaux, Charles, Fasquelle, Corinne, Géron, Sarah, Tamma, Nico, Zhang, Zhiyan, Coppieters, Wouter, Georges, Michel, Charlier, Carole
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305398/ https://www.ncbi.nlm.nih.gov/pubmed/22438830 http://dx.doi.org/10.1371/journal.pgen.1002581

Ejemplares similares

Genome-wide next-generation DNA and RNA sequencing reveals a mutation that perturbs splicing of the phosphatidylinositol glycan anchor biosynthesis class H gene (PIGH) and causes arthrogryposis in Belgian Blue cattle
por: Sartelet, Arnaud, et al.
Publicado: (2015)

Balancing Selection of a Frame-Shift Mutation in the MRC2 Gene Accounts for the Outbreak of the Crooked Tail Syndrome in Belgian Blue Cattle
por: Fasquelle, Corinne, et al.
Publicado: (2009)

A missense mutation accelerating the gating of the lysosomal Cl(−)/H(+)-exchanger ClC-7/Ostm1 causes osteopetrosis with gingival hamartomas in cattle
por: Sartelet, Arnaud, et al.
Publicado: (2014)

Selection in action: dissecting the molecular underpinnings of the increasing muscle mass of Belgian Blue Cattle
por: Druet, Tom, et al.
Publicado: (2014)

Genetic Variants in REC8, RNF212, and PRDM9 Influence Male Recombination in Cattle
por: Sandor, Cynthia, et al.
Publicado: (2012)

A Deletion in the Bovine FANCI Gene Compromises Fertility by Causing Fetal Death and Brachyspina
por: Charlier, Carole, et al.
Publicado: (2012)

NGS-based reverse genetic screen for common embryonic lethal mutations compromising fertility in livestock
por: Charlier, Carole, et al.
Publicado: (2016)

Coding and noncoding variants in HFM1, MLH3, MSH4, MSH5, RNF212, and RNF212B affect recombination rate in cattle
por: Kadri, Naveen Kumar, et al.
Publicado: (2016)

Mapping QTL influencing gastrointestinal nematode burden in Dutch Holstein-Friesian dairy cattle
por: Coppieters, Wouter, et al.
Publicado: (2009)

High-resolution structural variants catalogue in a large-scale whole genome sequenced bovine family cohort data
por: Lee, Young-Lim, et al.
Publicado: (2023)

Patrocles: a database of polymorphic miRNA-mediated gene regulation in vertebrates
por: Hiard, Samuel, et al.
Publicado: (2010)

Sequenced-based GWAS for linear classification traits in Belgian Blue beef cattle reveals new coding variants in genes regulating body size in mammals
por: Gualdrón Duarte, José Luis, et al.
Publicado: (2023)

RNF11 at the Crossroads of Protein Ubiquitination
por: Mattioni, Anna, et al.
Publicado: (2020)

A 12 kb multi-allelic copy number variation encompassing a GC gene enhancer is associated with mastitis resistance in dairy cattle
por: Lee, Young-Lim, et al.
Publicado: (2021)

RNF8 - The Achilles heel of DNA repair when splicing rules
por: Pederiva, Chiara, et al.
Publicado: (2018)

Benchmarking phasing software with a whole-genome sequenced cattle pedigree
por: Oget-Ebrad, Claire, et al.
Publicado: (2022)

RNF11, a new piece in the A20 puzzle
por: Jacque, Emilie, et al.
Publicado: (2009)

A high density linkage map of the bovine genome
por: Arias, Juan A, et al.
Publicado: (2009)

The Role of Tissue-Specific Ubiquitin Ligases, RNF183, RNF186, RNF182 and RNF152, in Disease and Biological Function
por: Okamoto, Takumi, et al.
Publicado: (2020)

The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR
por: Scharaw, Sandra, et al.
Publicado: (2016)

Characterization of the RnfB and RnfG Subunits of the Rnf Complex from the Archaeon Methanosarcina acetivorans
por: Suharti, Suharti, et al.
Publicado: (2014)

Abnormal splicing switch of DMD's penultimate exon compromises muscle fibre maintenance in myotonic dystrophy
por: Rau, Frédérique, et al.
Publicado: (2015)

Neuronal RING finger protein 11 (RNF11) regulates canonical NF-κB signaling
por: Pranski, Elaine L, et al.
Publicado: (2012)

AKAP12 and RNF11 as Diagnostic Markers of Fibromyalgia and Their Correlation with Immune Infiltration
por: Lin, Xiaowen, et al.
Publicado: (2022)

Downregulation of splicing regulator RBFOX1 compromises visual depth perception
por: Gu, Lei, et al.
Publicado: (2018)

An evaluation of inbreeding measures using a whole-genome sequenced cattle pedigree
por: Alemu, Setegn Worku, et al.
Publicado: (2020)

The RNF20/40 complex regulates p53-dependent gene transcription and mRNA splicing
por: Wu, Chen, et al.
Publicado: (2019)

RNF126 Quenches RNF168 Function in the DNA Damage Response
por: Zhang, Lianzhong, et al.
Publicado: (2018)

Performances of Adaptive MultiBLUP, Bayesian regressions, and weighted-GBLUP approaches for genomic predictions in Belgian Blue beef cattle
por: Gualdrón Duarte, José Luis, et al.
Publicado: (2020)

Can the Ceftriaxone Breakpoints Be Increased Without Compromising Patient Outcomes?
por: Tamma, Pranita D, et al.
Publicado: (2018)

ALS-Associated FUS Mutations Result in Compromised FUS Alternative Splicing and Autoregulation
por: Zhou, Yueqin, et al.
Publicado: (2013)

SNP-based quantitative deconvolution of biological mixtures: application to the detection of cows with subclinical mastitis by whole-genome sequencing of tank milk
por: Coppieters, Wouter, et al.
Publicado: (2020)

Fast Homozygosity Mapping and Identification of a Zebrafish ENU-Induced Mutation by Whole-Genome Sequencing
por: Voz, Marianne L., et al.
Publicado: (2012)

CLK2 blockade modulates alternative splicing compromising MYC‐driven breast tumors
por: Salvador, Fernando, et al.
Publicado: (2018)

LncRNA RNF144A-AS1 Promotes Bladder Cancer Progression via RNF144A-AS1/miR-455-5p/SOX11 Axis
por: Bi, Huifeng, et al.
Publicado: (2020)

Calling RNF168 to action
por: Nowsheen, Somaira, et al.
Publicado: (2018)

High male specific contribution of the X-chromosome to individual global recombination rate in dairy cattle
por: Kadri, N. K., et al.
Publicado: (2022)

BCL10 regulates RNF8/RNF168-mediated ubiquitination in the DNA damage response
por: Zhao, Hongchang, et al.
Publicado: (2014)

MRE11 and UBR5 Co-Operate to Suppress RNF168-Mediated Fusion of Dysfunctional Telomeres
por: Tang, Yongjian, et al.
Publicado: (2021)

A Triad of Highly Divergent Polymeric Immunoglobulin Receptor (PIGR) Haplotypes with Major Effect on IgA Concentration in Bovine Milk
por: Berry, Sarah, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_jolodok99kbavcpqjmot460aup