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The Yeast Forkhead Transcription Factors Fkh1 and Fkh2 Regulate Lifespan and Stress Response Together with the Anaphase-Promoting Complex

Forkhead box O (FOXO) transcription factors have a conserved function in regulating metazoan lifespan. A key function in this process involves the regulation of the cell cycle and stress responses including free radical scavenging. We employed yeast chronological and replicative lifespan assays, as...

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Detalles Bibliográficos
Autores principales: Postnikoff, Spike D. L., Malo, Mackenzie E., Wong, Berchman, Harkness, Troy A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305399/
https://www.ncbi.nlm.nih.gov/pubmed/22438832
http://dx.doi.org/10.1371/journal.pgen.1002583