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Mouse Genetics Suggests Cell-Context Dependency for Myc-Regulated Metabolic Enzymes during Tumorigenesis
c-Myc (hereafter called Myc) belongs to a family of transcription factors that regulates cell growth, cell proliferation, and differentiation. Myc initiates the transcription of a large cast of genes involved in cell growth by stimulating metabolism and protein synthesis. Some of these, like those i...
Autores principales: | Nilsson, Lisa M., Plym Forshell, Tacha Zi, Rimpi, Sara, Kreutzer, Christiane, Pretsch, Walter, Bornkamm, Georg W., Nilsson, Jonas A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305401/ https://www.ncbi.nlm.nih.gov/pubmed/22438825 http://dx.doi.org/10.1371/journal.pgen.1002573 |
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