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Carrageenan induced phosphorylation of Akt is dependent on neurokinin-1 expressing neurons in the superficial dorsal horn

BACKGROUND: Paw carrageenan induces activation of phosphatidylinositol 3-kinase (PI-3K) and Akt in dorsal horn neurons in addition to induction of pain behavior. Spinal PI-3K activation is also thought to be required for inflammation-induced trafficking of GluA1, AMPA receptor subunits, into plasma...

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Detalles Bibliográficos
Autores principales:	Choi, Jeong IL, Koehrn, Fred J, Sorkin, Linda S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305429/ https://www.ncbi.nlm.nih.gov/pubmed/22243518 http://dx.doi.org/10.1186/1744-8069-8-4

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