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TGF-β1 Down-Regulation of NKG2D/DAP10 and 2B4/SAP Expression on Human NK Cells Contributes to HBV Persistence
The mechanism underlying persistent hepatitis B virus (HBV) infection remains unclear. We investigated the role of innate immune responses to persistent HBV infection in 154 HBV-infected patients and 95 healthy controls. The expression of NKG2D- and 2B4-activating receptors on NK cells was significa...
Autores principales: | Sun, Cheng, Fu, Binqing, Gao, Yufeng, Liao, Xiaofeng, Sun, Rui, Tian, Zhigang, Wei, Haiming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305436/ https://www.ncbi.nlm.nih.gov/pubmed/22438812 http://dx.doi.org/10.1371/journal.ppat.1002594 |
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