Identification of genetic risk variants for deep vein thrombosis by multiplexed next-generation sequencing of 186 hemostatic/pro-inflammatory genes

BACKGROUND: Next-generation DNA sequencing is opening new avenues for genetic association studies in common diseases that, like deep vein thrombosis (DVT), have a strong genetic predisposition still largely unexplained by currently identified risk variants. In order to develop sequencing and analyti...

Descripción completa

Detalles Bibliográficos
Autores principales: Lotta, Luca A, Wang, Mark, Yu, Jin, Martinelli, Ida, Yu, Fuli, Passamonti, Serena M, Consonni, Dario, Pappalardo, Emanuela, Menegatti, Marzia, Scherer, Steven E, Lewis, Lora L, Akbar, Humeira, Wu, Yuanqing, Bainbridge, Matthew N, Muzny, Donna M, Mannucci, Pier M, Gibbs, Richard A, Peyvandi, Flora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305575/
https://www.ncbi.nlm.nih.gov/pubmed/22353194
http://dx.doi.org/10.1186/1755-8794-5-7

Ejemplares similares

Ejemplares similares