Impact of complex NOTCH1 mutations on survival in paediatric T-cell leukaemia

BACKGROUND: Molecular alterations occur frequently in T-ALL and the potential impact of those abnormalities on outcome is still controversial. The current study aimed to test whether NOTCH1 mutations and additional molecular abnormalities would impact T-ALL outcome in a series of 138 T-ALL paediatri...

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Detalles Bibliográficos
Autores principales: Mansur, Marcela Braga, Hassan, Rocio, Barbosa, Thayana C, Splendore, Alessandra, Jotta, Patricia Y, Yunes, José Andrés, Wiemels, Joseph L, Pombo-de-Oliveira, Maria S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305583/
https://www.ncbi.nlm.nih.gov/pubmed/22225590
http://dx.doi.org/10.1186/1471-2407-12-9

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