Cargando…

Regulatory interactions for iron homeostasis in Aspergillus fumigatus inferred by a Systems Biology approach

BACKGROUND: In System Biology, iterations of wet-lab experiments followed by modelling approaches and model-inspired experiments describe a cyclic workflow. This approach is especially useful for the inference of gene regulatory networks based on high-throughput gene expression data. Experiments can...

Descripción completa

Detalles Bibliográficos
Autores principales:	Linde, Jörg, Hortschansky, Peter, Fazius, Eugen, Brakhage, Axel A, Guthke, Reinhard, Haas, Hubertus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305660/ https://www.ncbi.nlm.nih.gov/pubmed/22260221 http://dx.doi.org/10.1186/1752-0509-6-6

Ejemplares similares

Iron homeostasis—Achilles’ heel of Aspergillus fumigatus?
por: Schrettl, Markus, et al.
Publicado: (2011)

Azole Resistance-Associated Regulatory Motifs within the Promoter of cyp51A in Aspergillus fumigatus
por: Kühbacher, Alexander, et al.
Publicado: (2022)

The bZIP Transcription Factor HapX Is Post-Translationally Regulated to Control Iron Homeostasis in Aspergillus fumigatus
por: López-Berges, Manuel Sánchez, et al.
Publicado: (2021)

Integrative analysis of the heat shock response in Aspergillus fumigatus
por: Albrecht, Daniela, et al.
Publicado: (2010)

The monothiol glutaredoxin GrxD is essential for sensing iron starvation in Aspergillus fumigatus
por: Misslinger, Matthias, et al.
Publicado: (2019)

Network Modeling Reveals Cross Talk of MAP Kinases during Adaptation to Caspofungin Stress in Aspergillus fumigatus
por: Altwasser, Robert, et al.
Publicado: (2015)

Automated Image Analysis of the Host-Pathogen Interaction between Phagocytes and Aspergillus fumigatus
por: Mech, Franziska, et al.
Publicado: (2011)

SreA-mediated iron regulation in Aspergillus fumigatus
por: Schrettl, Markus, et al.
Publicado: (2008)

Structural basis of HapE(P88L)-linked antifungal triazole resistance in Aspergillus fumigatus
por: Hortschansky, Peter, et al.
Publicado: (2020)

Iron – A Key Nexus in the Virulence of Aspergillus fumigatus
por: Haas, Hubertus
Publicado: (2012)

Riboflavin and pantothenic acid biosynthesis are crucial for iron homeostasis and virulence in the pathogenic mold Aspergillus fumigatus
por: Dietl, Anna-Maria, et al.
Publicado: (2018)

Regulation of Sulphur Assimilation Is Essential for Virulence and Affects Iron Homeostasis of the Human-Pathogenic Mould Aspergillus fumigatus
por: Amich, Jorge, et al.
Publicado: (2013)

The Zn(2)Cys(6)-type transcription factor LeuB cross-links regulation of leucine biosynthesis and iron acquisition in Aspergillus fumigatus
por: Long, Nanbiao, et al.
Publicado: (2018)

HapX-Mediated Adaption to Iron Starvation Is Crucial for Virulence of Aspergillus fumigatus
por: Schrettl, Markus, et al.
Publicado: (2010)

Ambient Availability of Amino Acids, Proteins, and Iron Impacts Copper Resistance of Aspergillus fumigatus
por: Yap, Annie, et al.
Publicado: (2022)

Comparison of transcriptome technologies in the pathogenic fungus Aspergillus fumigatus reveals novel insights into the genome and MpkA dependent gene expression
por: Müller, Sebastian, et al.
Publicado: (2012)

The metalloreductase FreB is involved in adaptation of Aspergillus fumigatus to iron starvation
por: Blatzer, Michael, et al.
Publicado: (2011)

The MAP kinase MpkA controls cell wall integrity, oxidative stress response, gliotoxin production and iron adaptation in Aspergillus fumigatus
por: Jain, Radhika, et al.
Publicado: (2011)

Iron-sensing is governed by mitochondrial, not by cytosolic iron–sulfur cluster biogenesis in Aspergillus fumigatus
por: Misslinger, Matthias, et al.
Publicado: (2018)

The Siderophore Ferricrocin Mediates Iron Acquisition in Aspergillus fumigatus
por: Happacher, Isidor, et al.
Publicado: (2023)

Pseudomonas aeruginosa manipulates redox and iron homeostasis of its microbiota partner Aspergillus fumigatus via phenazines
por: Briard, Benoit, et al.
Publicado: (2015)

Fungal siderophore metabolism with a focus on Aspergillus fumigatus
por: Haas, Hubertus
Publicado: (2014)

Siderophore Biosynthesis But Not Reductive Iron Assimilation Is Essential for Aspergillus fumigatus Virulence
por: Schrettl, Markus, et al.
Publicado: (2004)

Module-detection approaches for the integration of multilevel omics data highlight the comprehensive response of Aspergillus fumigatus to caspofungin
por: Conrad, T., et al.
Publicado: (2018)

Draft Genome Sequences of Fungus Aspergillus calidoustus
por: Horn, Fabian, et al.
Publicado: (2016)

SREBP Coordinates Iron and Ergosterol Homeostasis to Mediate Triazole Drug and Hypoxia Responses in the Human Fungal Pathogen Aspergillus fumigatus
por: Blatzer, Michael, et al.
Publicado: (2011)

Histidine biosynthesis plays a crucial role in metal homeostasis and virulence of Aspergillus fumigatus
por: Dietl, Anna-Maria, et al.
Publicado: (2016)

Additional oxidative stress reroutes the global response of Aspergillus fumigatus to iron depletion
por: Kurucz, Vivien, et al.
Publicado: (2018)

The leucine biosynthetic pathway is crucial for adaptation to iron starvation and virulence in Aspergillus fumigatus
por: Orasch, Thomas, et al.
Publicado: (2019)

Regulatory network modelling of iron acquisition by a fungal pathogen in contact with epithelial cells
por: Linde, Jörg, et al.
Publicado: (2010)

Interference of Aspergillus fumigatus with the immune response
por: Heinekamp, Thorsten, et al.
Publicado: (2014)

Isolation and immunofluorescence staining of Aspergillus fumigatus conidia-containing phagolysosomes
por: Goldmann, Marie, et al.
Publicado: (2021)

Iron acquisition and oxidative stress response in aspergillus fumigatus
por: Brandon, Madison, et al.
Publicado: (2015)

Aspergillus fumigatus versus Genus Aspergillus: Conservation, Adaptive Evolution and Specific Virulence Genes
por: Gupta, Shishir K., et al.
Publicado: (2021)

Prediction and validation of host-pathogen interactions by a versatile inference approach using Aspergillus fumigatus as a case study
por: Balkenhol, Johannes, et al.
Publicado: (2022)

Analysis of the Aspergillus fumigatus Proteome Reveals Metabolic Changes and the Activation of the Pseurotin A Biosynthesis Gene Cluster in Response to Hypoxia
por: Vödisch, Martin, et al.
Publicado: (2011)

HapX Mediates Iron Homeostasis in the Pathogenic Dermatophyte Arthroderma benhamiae but Is Dispensable for Virulence
por: Kröber, Antje, et al.
Publicado: (2016)

High‐Throughput Gene Replacement in Aspergillus fumigatus
por: Zhao, Can, et al.
Publicado: (2019)

Aspf2 From Aspergillus fumigatus Recruits Human Immune Regulators for Immune Evasion and Cell Damage
por: Dasari, Prasad, et al.
Publicado: (2018)

Aspergillus fumigatus melanins: interference with the host endocytosis pathway and impact on virulence
por: Heinekamp, Thorsten, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_mcckek8cptt63pdoje3qdvtna6