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Automatic identification and normalization of dosage forms in drug monographs

BACKGROUND: Each day, millions of health consumers seek drug-related information on the Web. Despite some efforts in linking related resources, drug information is largely scattered in a wide variety of websites of different quality and credibility. METHODS: As a step toward providing users with int...

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Autores principales: Li, Jiao, Lu, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305679/
https://www.ncbi.nlm.nih.gov/pubmed/22336431
http://dx.doi.org/10.1186/1472-6947-12-9
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author Li, Jiao
Lu, Zhiyong
author_facet Li, Jiao
Lu, Zhiyong
author_sort Li, Jiao
collection PubMed
description BACKGROUND: Each day, millions of health consumers seek drug-related information on the Web. Despite some efforts in linking related resources, drug information is largely scattered in a wide variety of websites of different quality and credibility. METHODS: As a step toward providing users with integrated access to multiple trustworthy drug resources, we aim to develop a method capable of identifying drug's dosage form information in addition to drug name recognition. We developed rules and patterns for identifying dosage forms from different sections of full-text drug monographs, and subsequently normalized them to standardized RxNorm dosage forms. RESULTS: Our method represents a significant improvement compared with a baseline lookup approach, achieving overall macro-averaged Precision of 80%, Recall of 98%, and F-Measure of 85%. CONCLUSIONS: We successfully developed an automatic approach for drug dosage form identification, which is critical for building links between different drug-related resources.
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spelling pubmed-33056792012-03-16 Automatic identification and normalization of dosage forms in drug monographs Li, Jiao Lu, Zhiyong BMC Med Inform Decis Mak Research Article BACKGROUND: Each day, millions of health consumers seek drug-related information on the Web. Despite some efforts in linking related resources, drug information is largely scattered in a wide variety of websites of different quality and credibility. METHODS: As a step toward providing users with integrated access to multiple trustworthy drug resources, we aim to develop a method capable of identifying drug's dosage form information in addition to drug name recognition. We developed rules and patterns for identifying dosage forms from different sections of full-text drug monographs, and subsequently normalized them to standardized RxNorm dosage forms. RESULTS: Our method represents a significant improvement compared with a baseline lookup approach, achieving overall macro-averaged Precision of 80%, Recall of 98%, and F-Measure of 85%. CONCLUSIONS: We successfully developed an automatic approach for drug dosage form identification, which is critical for building links between different drug-related resources. BioMed Central 2012-02-15 /pmc/articles/PMC3305679/ /pubmed/22336431 http://dx.doi.org/10.1186/1472-6947-12-9 Text en Copyright ©2012 Li and Lu et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Li, Jiao
Lu, Zhiyong
Automatic identification and normalization of dosage forms in drug monographs
title Automatic identification and normalization of dosage forms in drug monographs
title_full Automatic identification and normalization of dosage forms in drug monographs
title_fullStr Automatic identification and normalization of dosage forms in drug monographs
title_full_unstemmed Automatic identification and normalization of dosage forms in drug monographs
title_short Automatic identification and normalization of dosage forms in drug monographs
title_sort automatic identification and normalization of dosage forms in drug monographs
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305679/
https://www.ncbi.nlm.nih.gov/pubmed/22336431
http://dx.doi.org/10.1186/1472-6947-12-9
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